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UDCA Specifications
Other name: Tauroursodiol,Urosodeoxycholic Acid, Ursodiol
CAS No.: 128-13-2
MF: C24H40O4
MW: 392.57
EINECS: 204-879-3
Purity: 99%
Appearance: White crystalline powder
UDCA Description
Ursodeoxycholic Acid, also known as UDCA or ursodiol, is a secondary bile acid found in small quantities in human bile. However, in medicinal formulations, UDCA is derived from synthetic or bear bile sources. It is renowned for its unique properties that aid in reducing cholesterol levels in bile, protecting liver cells, and assisting in the dissolution of certain gallstones.
How Does Ursodeoxycholic Acid Work?
UDCA's mechanism of action revolves around its dual benefits for liver health. Firstly, it helps to promote the flow of bile, reducing cholesterol saturation in the gallbladder, and preventing the formation of cholesterol-based gallstones. Secondly, UDCA exhibits cytoprotective properties, which means it safeguards liver cells from damage, inflammation, and apoptosis, thus supporting overall liver function.
Ursodeoxycholic Acid Benefits
Gallstone Management
Ursodeoxycholic Acid is effective in dissolving small cholesterol gallstones, reducing the need for surgical interventions and facilitating a safer, non-invasive approach to gallstone management.
Primary Biliary Cholangitis (PBC)
UDCA is the primary treatment for PBC, an autoimmune liver disease. It helps slow disease progression, improve liver function, and enhance patients' quality of life.
Non-alcoholic Fatty Liver Disease (NAFLD)
UDCA shows promise in NAFLD treatment, assisting in reducing liver fat content and inflammation, potentially preventing disease progression.
Liver Protection
The cytoprotective properties of Ursodeoxycholic Acid make it an essential component in liver protection and regeneration strategies.
Cholesterol Reduction
UDCA can effectively lower serum cholesterol levels, making it beneficial for individuals with certain cholesterol-related conditions.