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Raloxifene Hydrochloride Specifications
Other name: Raloxifene HCl, Evista
CAS: 82640-04-8
MF: C28H28ClNO4S
MW: 510.04
Purity: 99%
Appearance: Off-white or pale yellow crystalline powder
Raloxifene Hydrochloride/Raloxifene HCL Description
Raloxifene HCl is in a class of medications called selective estrogen receptor modulators (SERMs). Raloxifene hydrochloride acts as an anti-estrogen in both breast and uterine tissue while being estrogenic in bone. Raloxifene Hcl have efficacy against estrogen-sensitive cancers.
Raloxifene Hcl is an estrogen agonist antagonist, referred to as a selective estrogen receptor modulator and belongs to the benzothiophene class of compounds. The Raloxifene Hcl biological actions are largely mediated through binding to estrogen receptors, and it binding results in activation of estrogenic pathways in some tissues Agonism and and the blockade of estrogenic pathways in Antagonism.
Raloxifene (marketed as Evista) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer. Raloxifene hydrochloride is approved to prevent Breast cancer. It is used to decrease the chance of invasive breast cancer in postmenopausal women who have a high risk for developing the disease or who have osteoporosis.
Raloxifene Hydrochloride Recommended Dosage
Raloxifene Hcl recommended initial dose is one 60 mg tablet daily. It may administered any time of day without regard to meals.
The usual adult dose is one tablet (37.5 mg) daily, administered before breakfast or 1-2 hours after breakfast. Bodybuilder dosage recommendations are consistent with those of patients, and should be individualized to obtain an adequate response with the lowest effective dose.
For some patients or bodybuilders half a tablet (18.75 mg) daily may be adequate, while others might take half a dose twice daily.
